Details

Autor(en) / Beteiligte

• Gransier, Robin
• Hofmann, Michael
• van Wieringen, Astrid
• Wouters, Jan

Titel

Stimulus-evoked phase-locked activity along the human auditory pathway strongly varies across individuals

Ist Teil von

• Scientific reports, 2021-01, Vol.11 (1), p.143-143, Article 143

Ort / Verlag

England: Nature Publishing Group

Erscheinungsjahr

2021

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Phase-locking to the temporal envelope of speech is associated with envelope processing and speech perception. The phase-locked activity of the auditory pathway, across modulation frequencies, is generally assessed at group level and shows a decrease in response magnitude with increasing modulation frequency. With the exception of increased activity around 40 and 80 to 100 Hz. Furthermore, little is known about the phase-locked response patterns to modulation frequencies ≤ 20 Hz, which are modulations predominately present in the speech envelope. In the present study we assess the temporal modulation transfer function (TMTF ) of the phase-locked activity of the auditory pathway, from 0.5 to 100 Hz at a high-resolution and by means of auditory steady-state responses. Although the group-averaged TMTF corresponds well with those reported in the literature, the individual TMTF shows a remarkable intersubject variability. This intersubject variability is especially present for ASSRs that originate from the cortex and are evoked with modulation frequencies ≤ 20 Hz. Moreover, we found that these cortical phase-locked activity patterns are robust over time. These results show the importance of the individual TMTF when assessing phase-locked activity to envelope fluctuations, which can potentially be used as a marker for auditory processing.