Molecules (Basel, Switzerland), 2017-01, Vol.22 (1), p.94-94
2017
Details
- Autor(en) / Beteiligte
- Titel
- Alkaloids and Phenolic Compounds from Sida rhombifolia L. (Malvaceae) and Vasorelaxant Activity of Two Indoquinoline Alkaloids
- Ist Teil von
- Molecules (Basel, Switzerland), 2017-01, Vol.22 (1), p.94-94
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2017
- Link zum Volltext
- Quelle
- Elektronische Zeitschriftenbibliothek (Open access)
- Beschreibungen/Notizen
- The follow-up of phytochemical and pharmacological studies of L. (Malvaceae) aims to strengthen the chemosystematics and pharmacology of genera and support the ethnopharmacological use of this species as hypotensive herb. The present work reports phytoconstituents isolated and identified from aerial parts of by using chromatographic and spectroscopic methods. The study led to the isolation of scopoletin ( ), scoporone ( ), ethoxy-ferulate ( ), kaempferol ( ), kaempferol-3- -β-d-glycosyl-6''-α-d-rhamnose ( ), quindolinone ( ), 11-methoxy-quindoline ( ), quindoline ( ), and the cryptolepine salt ( ). The alkaloids quindolinone ( ) and cryptolepine salt ( ) showed vasorelaxant activity in rodent isolated mesenteric arteries.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1420-3049eISSN: 1420-3049DOI: 10.3390/molecules22010094Titel-ID: cdi_doaj_primary_oai_doaj_org_article_35a5c688b65846e4a50f1971c5a89559
- Format
- –
- Schlagworte
- Agreements, Alkaloids, Alkaloids - chemistry, Alkaloids - isolation & purification, Alkaloids - pharmacology, Animals, Antihypertensive Agents - chemistry, Antihypertensive Agents - isolation & purification, Antihypertensive Agents - pharmacology, Arteries, Coumarins - chemistry, Coumarins - isolation & purification, Coumarins - pharmacology, D-Rhamnose, Dose-Response Relationship, Drug, Flavonoids - chemistry, Flavonoids - isolation & purification, Flavonoids - pharmacology, Humans, Hypertension, indoquinoline alkaloids, Kaempferol, Malvaceae, Malvaceae - chemistry, Mesenteric Arteries - drug effects, Mesenteric Arteries - physiology, Pharmacology, Phenolic compounds, Phenols, Phenols - chemistry, Phenols - isolation & purification, Phenols - pharmacology, Phytochemicals, Phytochemicals - chemistry, Phytochemicals - isolation & purification, Phytochemicals - pharmacology, Plant Components, Aerial - chemistry, Plant Extracts - chemistry, Rats, Rhamnose, Salts, Sida rhombifolia, Spectroscopic analysis, Tissue Culture Techniques, Vasodilator Agents - chemistry, Vasodilator Agents - isolation & purification, Vasodilator Agents - pharmacology, vasorelaxant activity