Details

Autor(en) / Beteiligte

• Boogaart, T. van den
• Lomonossoff, G.P
• Davies, J.W

Titel

Can we explain RNA-mediated virus resistance by homology-dependent gene silencing?

Ist Teil von

• Molecular plant-microbe interactions, 1998-07, Vol.11 (7), p.717-723

Ort / Verlag

St Paul, MN: APS Press

Erscheinungsjahr

1998

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The use of viral sequences to produce virus-resistant plants is now almost a standard technique. A variety of sequences from a large number of viruses have been used but the mechanisms remain largely unknown. There are probably at least two distinct types of mechanisms operating: one requiring the expression of the viral protein(s) and the other dependent only on the presence of transgene-derived RNA. In this review, we will discuss this RNA-mediated resistance and its similarities with co-suppression, a recently described phenomenon leading to suppression of transgene expression and homologous sequences. We present a critical view of the current models available to explain this type of resistance