Details

Autor(en) / Beteiligte

• Beltrão, E I C
• Medeiros, P L
• Rodrigues, O G
• Figueredo-Silva, J
• Valença, M M
• Coelho, L C B B
• Carvalho, Jr, L B

Titel

Parkia pendula lectin as histochemistry marker for meningothelial tumour

Ist Teil von

• European journal of histochemistry, 2003, Vol.47 (2), p.139-142

Ort / Verlag

Italy: PAGEPress Publications

Erscheinungsjahr

2003

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Lectins have been intensively used in histochemical techniques for cell surface characterization. These proteins are involved in several biological processes and their use as histochemical markers have been evaluated since they can indicate differences in cell surfaces. Parkia pendula lectin (PpeL) was evaluated as histochemical marker for meningothelial meningioma biopsies. Tissue slices were incubated with PpeL conjugated to horseradish peroxidase (PpeL-HRP) and Concanavalin A-HRP (ConA-HPR) and the binding visualized with diaminobenzidine and hydrogen peroxide. The lectin-tissue binding was inhibited with D-glucose. PpeL showed to be a useful tool for the characterization of meningothelial tumour and clinico-pathological diagnosis.