Details

Autor(en) / Beteiligte

• Ogawa, Haruhiko
• Fujimura, Masaki
• Ohkura, Noriyuki
• Makimura, Koichi

Titel

A Proposal of Guidance for Identification of Schizophyllum commune-Associated Sinobronchial Allergic Mycosis

Ist Teil von

• Allergology International, 2014, Vol.63 (2), p.287-288

Ort / Verlag

England: JAPANESE SOCIETY OF ALLERGOLOGY

Erscheinungsjahr

2014

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Our recent studies suggested that Schizophyllum commune, which is a basidiomycetous (BM) fungus that can cause allergic bronchopulmonary mycosis (ABPM) and allergic fungal rhinosinusitis (AFRS), is an important organism that acts as a causative fungal antigen and is a candidate organism influencing the clinical manifestations of asthma via sensitization to this fungus. This environmental fungus is likely to be closely related to allergic fungal respiratory disease (AFRD). When unknown samples or plural eumycetes are cultured from bronchial materials from patient with mucoid impaction of the bronchi (MIB), a definitive diagnosis of ABPM cannot be made without positive findings of an allergic reaction against the identified fungi. Similarly, a positive allergic reaction is necessary to make a definite diagnosis of AFRS in patients with chronic rhinosinusitis (CRS). Antigen inhalation test for definitive diagnosis of ABPM caused by S.commune is not commonly used in most clinics; however, even skin tests cannot be performed easily without use of S.commune antigenic solution. Therefore, some authors have proposed removing type I hypersensitivity from the diagnostic criteria for AFRS.