Details

Autor(en) / Beteiligte

• Jones, T. W.
• Eddens, L.
• Kupusarevic, J.
• Simoes, D. C. M.
• Furber, M. J. W.
• van Someren, K. A.
• Howatson, G.

Titel

Aerobic exercise intensity does not affect the anabolic signaling following resistance exercise in endurance athletes

Ist Teil von

• Scientific reports, 2021-05, Vol.11 (1), p.10785-10785, Article 10785

Ort / Verlag

London: Nature Publishing Group

Erscheinungsjahr

2021

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Abstract This study examined whether intensity of endurance stimulus within a concurrent training paradigm influenced the phosphorylation of signaling proteins associated with the mTOR and AMPK networks. Eight male cyclists completed (1) resistance exercise (RES), 6 × 8 squats at 80% 1-RM; (2) resistance exercise and moderate intensity cycling of 40 min at 65% V̇O 2peak , (RES + MIC); (3) resistance exercise and high intensity interval cycling of 40 min with 6 alternating 3 min intervals of 85 and 45% V̇O 2peak (RES + HIIC), in a cross-over design. Muscle biopsies were collected at rest and 3 h post-RES. There was a main effect of condition for mTOR S2448 ( p  = 0.043), with a greater response in the RES + MIC relative to RES condition ( p  = 0.033). There was a main effect of condition for AMPKα2 T172 ( p  = 0.041), with a greater response in RES + MIC, relative to both RES + HIIC ( p  = 0.026) and RES ( p  = 0.046). There were no other condition effects for the remaining protein kinases assessed ( p  > 0.05). These data do not support a molecular interference effect in cyclists under controlled conditions. There was no intensity-dependent regulation of AMPK, nor differential activation of anabolism with the manipulation of endurance exercise intensity.