Details

Autor(en) / Beteiligte

• Testa, Luca
• Popolo Rubbio, Antonio
• Squillace, Mattia
• Albano, Flavio
• Cesario, Vincenzo
• Casenghi, Matteo
• Tarantini, Giuseppe
• Pagnotta, Paolo
• Ielasi, Alfonso
• Popusoi, Grigore
• Paloscia, Leonardo
• Durante, Alessandro
• Maffeo, Diego
• Meucci, Francesco
• Valentini, Giuliano
• Ussia, Gian Paolo
• Cioffi, Paolo
• Cortese, Bernardo
• Sangiorgi, Giuseppe
• Contegiacomo, Gaetano
• Bedogni, Francesco

Titel

Patent foramen ovale occlusion with the Cocoon PFO Occluder. The PROS-IT collaborative project

Ist Teil von

• Frontiers in cardiovascular medicine, 2023-01, Vol.9, p.1064026-1064026

Ort / Verlag

Switzerland: Frontiers Media S.A

Erscheinungsjahr

2023

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The Cocoon patent foramen ovale (PFO) Occluder is a new generation nitinol alloy double-disk device coated with nanoplatinum, likely useful in patients with nickel hypersensitivity. Early results and mid-term outcomes of this device in percutaneous PFO closure are missing. To assess the preliminary efficacy and safety profile of PFO closure with Cocoon device in an Italian multi-center registry. This is a prospective registry of 189 consecutive adult patients treated with the Cocoon PFO Occluder at 15 Italian centers from May 2017 till May 2020. Patients were followed up for 2 years. Closure of the PFO with Cocoon Occluder was carried out successfully in all patients, with complete closure without residual shunt in 94.7% of the patients and minimal shunt in 5.3%. Except from a case of paroxysmal supraventricular tachycardia and a major vascular bleeding, no procedural and in-hospital device-related complications occurred. No patient developed cardiac erosions, allergic reactions to nickel, or any other major complications during the follow-up. During the follow-up period, 2 cases of new-onset atrial fibrillation occurred within thirty-day. Percutaneous closure of PFO with Cocoon Occluder provided satisfactory procedural and mid-term clinical follow-up results in a real-world registry.