Details

Autor(en) / Beteiligte

• Tresserra-Rimbau, Anna
• Castro-Barquero, Sara
• Becerra-Tomás, Nerea
• Babio, Nancy
• Martínez-González, Miguel Ángel
• Corella, Dolores
• Fitó, Montserrat
• Romaguera, Dora
• Vioque, Jesús
• Alonso-Gomez, Angel M
• Wärnberg, Julia
• Martínez, José Alfredo
• Serra-Majem, Luís
• Estruch, Ramon
• Tinahones, Francisco J
• Lapetra, José
• Pintó, Xavier
• Tur, Josep A
• López-Miranda, José
• Cano-Ibáñez, Naomi
• Delgado-Rodríguez, Miguel
• Matía-Martín, Pilar
• Daimiel, Lidia
• Martín Sánchez, Vicente
• Vidal, Josep
• Vázquez, Clotilde
• Ros, Emili
• Basterra, Francisco Javier
• Fernández de la Puente, María
• Asensio, Eva M
• Castañer, Olga
• Bullón-Vela, Vanessa
• Tojal-Sierra, Lucas
• Gómez-Gracia, Enrique
• Cases-Pérez, Eugenio
• Konieczna, Jadwiga
• García-Ríos, Antonio
• Casañas-Quintana, Tamara
• Bernal-Lopez, María Rosa
• Santos-Lozano, José Manuel
• Esteve-Luque, Virginia
• Bouzas, Cristina
• Vázquez-Ruiz, Zenaida
• Palau-Galindo, Antoni
• Barragan, Rocio
• López Grau, Mercè
• Razquín, Cristina
• Goicolea-Güemez, Leire
• Toledo, Estefanía
• Vergaz, Manel Vila
• Lamuela-Raventós, Rosa M
• Salas-Salvadó, Jordi

Titel

Adopting a High-Polyphenolic Diet Is Associated with an Improved Glucose Profile: Prospective Analysis within the PREDIMED-Plus Trial

Ist Teil von

• Antioxidants, 2022-02, Vol.11 (2), p.316

Ort / Verlag

Switzerland: MDPI AG

Erscheinungsjahr

2022

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Previous studies suggested that dietary polyphenols could reduce the incidence and complications of type-2 diabetes (T2D); although the evidence is still limited and inconsistent. This work analyzes whether changing to a diet with a higher polyphenolic content is associated with an improved glucose profile. At baseline, and at 1 year of follow-up visits, 5921 participants (mean age 65.0 ± 4.9, 48.2% women) who had overweight/obesity and metabolic syndrome filled out a validated 143-item semi-quantitative food frequency questionnaire (FFQ), from which polyphenol intakes were calculated. Energy-adjusted total polyphenols and subclasses were categorized in tertiles of changes. Linear mixed-effect models with random intercepts (the recruitment centers) were used to assess associations between changes in polyphenol subclasses intake and 1-year plasma glucose or glycosylated hemoglobin (HbA1c) levels. Increments in total polyphenol intake and some classes were inversely associated with better glucose levels and HbA1c after one year of follow-up. These associations were modified when the analyses were run considering diabetes status separately. To our knowledge, this is the first study to assess the relationship between changes in the intake of all polyphenolic groups and T2D-related parameters in a senior population with T2D or at high-risk of developing T2D.