International journal of molecular sciences, 2023-11, Vol.24 (22), p.16345
2023
Details
- Autor(en) / Beteiligte
- Titel
- Intravital Microscopy of Lipopolysaccharide-Induced Inflammatory Changes in Different Organ Systems—A Scoping Review
- Ist Teil von
- International journal of molecular sciences, 2023-11, Vol.24 (22), p.16345
- Ort / Verlag
- Basel: MDPI AG
- Erscheinungsjahr
- 2023
- Link zum Volltext
- Quelle
- EZB Electronic Journals Library
- Beschreibungen/Notizen
- Intravital microscopy (IVM) is a powerful imaging tool that captures biological processes in real-time. IVM facilitates the observation of complex cellular interactions in vivo, where ex vivo and in vitro experiments lack the physiological environment. IVM has been used in a multitude of studies under healthy and pathological conditions in different organ systems. IVM has become essential in the characterization of the immune response through visualization of leukocyte–endothelial interactions and subsequent changes within the microcirculation. Lipopolysaccharide (LPS), a common inflammatory trigger, has been used to induce inflammatory changes in various studies utilizing IVM. In this review, we provide an overview of IVM imaging of LPS-induced inflammation in different models, such as the brain, intestines, bladder, and lungs.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1422-0067, 1661-6596eISSN: 1422-0067DOI: 10.3390/ijms242216345Titel-ID: cdi_doaj_primary_oai_doaj_org_article_26487e1c68034ad8af2faf095d2ec8f0
- Format
- –
- Schlagworte
- Blood vessels, Endothelium, Gram-negative bacteria, Hazardous materials, Imaging systems, Immune response, Inflammation, intravital imaging, Leukocytes, Light, lipopolysaccharide, microcirculation, Microscope and microscopy, Microscopy, Permeability, Physiological aspects, Physiology, Sepsis, Visualization