Details

Autor(en) / Beteiligte

• Cheng, ZHONG
• WANG, Bin
• Sheng-qing LV

Titel

Application progress of temozolomide in clinical tumor chemotherapy

Ist Teil von

• Chinese Journal of Contemporary Neurology & Neurosurgery, 2013-12, Vol.13 (12), p.1044-1048

Ort / Verlag

Tianjin Shi: Tianjin Huanhu Hospital

Erscheinungsjahr

2013

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Temozolomide is an imidazotetrazine derivative of the alkylating agent, which is used to treat central nervous system tumors, especially malignant brain gliomas. It is a milestone in brain giloma chemotherapy. Recently, some researchers used temozolomide for the treatment of other tumors, including melanoma, intracranial metastatic tumors, lymphomas, refractory leukaemia, pituitary tumors, lung cancer, and so on. Some results are encouraging in clinical trials. Here, this paper makes a review on the antineoplastic mechanisms of temozolomide, its indications in gliomas and some unusual indications.