Details

Autor(en) / Beteiligte

• Tschandl, Philipp
• Gambardella, Alessio
• Boespflug, Amélie
• Deinlein, Teresa
• de Giorgi, Vincenzo
• Kittler, Harald
• Lallas, Aimilios
• Malvehy, Josep
• Moscarella, Elvira
• Puig, Susana
• Scalvenzi, Massimiliano
• Thomas, Luc
• Zalaudek, Iris
• Alfano, Roberto
• Argenziano, Giuseppe

Titel

Seven Non-melanoma Features to Rule Out Facial Melanoma

Ist Teil von

• Acta dermato-venereologica, 2017-11, Vol.97 (10), p.1219-1224

Ort / Verlag

Sweden: Medical Journals Sweden

Erscheinungsjahr

2017

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesions were evaluated for the prevalence (> 50% of lesional surface) of 7 dermatoscopic non-melanoma features: scales, white follicles, erythema/reticular vessels, reticular and/or curved lines/fingerprints, structureless brown colour, sharp demarcation, and classic criteria of seborrhoeic keratosis. Melanomas had a lower number of non-melanoma patterns (p< 0.001). Scoring a lesion suspicious when no prevalent non-melanoma pattern is found resulted in a sensitivity of 88.5% and a specificity of 66.9% for the diagnosis of melanoma. Specificity was higher for solar lentigo (78.8%) and seborrhoeic keratosis (74.3%) and lower for actinic keratosis (61.4%) and lichenoid keratosis (25.6%). Evaluation of prevalent non-melanoma patterns can provide slightly lower sensitivity and higher specificity in detecting facial melanoma compared with already known malignant features.