Details

Autor(en) / Beteiligte

• Chang, Rene Wei-Jung
• Chuang, Shu-Lin
• Hsu, Chen-Yang
• Yen, Amy Ming-Fang
• Wu, Wendy Yi-Ying
• Chen, Sam Li-Sheng
• Fann, Jean Ching-Yuan
• Tabar, Laszlo
• Smith, Robert A.
• Duffy, Stephen W.
• Chiu, Sherry Yueh-Hsia
• Chen, Hsiu-Hsi

Titel

Precision Science on Incidence and Progression of Early-Detected Small Breast Invasive Cancers by Mammographic Features

Ist Teil von

• Cancers, 2020-07, Vol.12 (7), p.1855

Ort / Verlag

Basel: MDPI AG

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Elektronische Zeitschriftenbibliothek - Freely accessible e-journals

Beschreibungen/Notizen

• The aim was to evaluate how the inter-screening interval affected the performance of screening by mammographic appearances. This was a Swedish retrospective screening cohort study with information on screening history and mammography features in two periods (1977–1985 and 1996–2010). The pre-clinical incidence and the mean sojourn time (MST) for small breast cancer allowing for sensitivity by mammographic appearances were estimated. The percentage of interval cancer against background incidence (I/E ratio) was used to assess the performance of mammography screening by different inter-screening intervals. The sensitivity-adjusted MSTs (in years) were heterogeneous with mammographic features, being longer for powdery and crushed stone-like calcifications (4.26, (95% CI, 3.50–5.26)) and stellate masses (3.76, (95% CI, 3.15–4.53)) but shorter for circular masses (2.65, (95% CI, 2.06–3.55)) in 1996–2010. The similar trends, albeit longer MSTs, were also noted in 1977–1985. The I/E ratios for the stellate type were 23% and 32% for biennial and triennial screening, respectively. The corresponding figures were 32% and 43% for the circular type and 21% and 29% for powdery and crushed stone-like calcifications, respectively. Mammography-featured progressions of small invasive breast cancer provides a new insight into personalized quality assurance, surveillance, treatment and therapy of early-detected breast cancer.