Details

Autor(en) / Beteiligte

• Balmpouzis, Zisis
• Faure van Rossum, Annabelle
• Baud, David
• Panchaud, Alice
• Mitropoulou, Georgia
• Mazza Stalder, Jesica
• Koutsokera, Angela

Titel

Successful pregnancy in a cystic fibrosis patient with a severe impairment of lung function receiving Elexacaftor-Tezacaftor-Ivacaftor

Ist Teil von

• Respiratory medicine case reports, 2022-01, Vol.40, p.101776, Article 101776

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2022

Quelle

ScienceDirect

Beschreibungen/Notizen

• Before the arrival of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulators women with CF and impaired lung function were experiencing a high risk of complications and mortality during and the years after pregnancy. The arrival of the highly efficient CFTR modulator, Elexacaftor-Tezacaftor-Ivacaftor (ETI) resulted in an improvement of lung function, quality of life and fertility. Here we report a case of successful pregnancy and uncomplicated delivery for a CF patient with severely impaired lung function receiving ETI prior to conception.