Details

Autor(en) / Beteiligte

• Pooladian, Faranak
• Escopy, Samira
• Demchenko, Alexei V.

Titel

Activation of Thioglycosides with Copper(II) Bromide

Ist Teil von

• Molecules (Basel, Switzerland), 2022-10, Vol.27 (21), p.7354

Ort / Verlag

Basel: MDPI AG

Erscheinungsjahr

2022

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Reported herein is a new protocol for glycosidation of alkyl and aryl thioglycosides in the presence of copper(II) bromide. While the activation with CuBr2 alone was proven suitable for reactive glycosyl donors, the activation of less reactive donors was more efficient in the presence of triflic acid as an additive. A variety of thioglycoside donors in reactions with different glycosyl acceptors were investigated to determine the initial scope of this reaction.