Details

Autor(en) / Beteiligte

• Leandro, Maria Karollyna do Nascimento Silva
• Moura, João Victor Barbosa
• Freire, Paulo de Tarso Cavalcante
• Vega, Maria Leticia
• Lima, Cleânio da Luz
• Hidalgo, Ángel Alberto
• Araújo, Ana Carolina Justino de
• Freitas, Priscilla Ramos
• Paulo, Cicera Laura Roque
• Sousa, Amanda Karine de
• Rocha, Janaina Esmeraldo
• Leandro, Lívia Maria Garcia
• Silva, Rakel Olinda Macedo da
• Cruz-Martins, Natália
• Coutinho, Henrique Douglas Melo

Titel

Characterization and Evaluation of Layered Bi2WO6 Nanosheets as a New Antibacterial Agent

Ist Teil von

• Antibiotics (Basel), 2021-09, Vol.10 (9), p.1068

Ort / Verlag

Basel: MDPI AG

Erscheinungsjahr

2021

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Background: Pathogenic microorganisms are causing increasing cases of mortality and morbidity, along with alarming rates of ineffectiveness as a result of acquired antimicrobial resistance. Bi2WO6 showed good potential to be used as an antibacterial substance when exposed to visible light. This study demonstrates for the first time the dimension-dependent antibacterial activity of layered Bi2WO6 nanosheets. Materials and methods: The synthesized layered Bi2WO6 nanosheets were prepared by the hydrothermal method and characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), atomic force microscopy (AFM), and Raman and Fourier transform infrared spectroscopy (FTIR). Antibacterial and antibiotic-modulation activities were performed in triplicate by the microdilution method associated with visible light irradiation (LEDs). Results: Bi2WO6 nanosheets were effective against all types of bacteria tested, with MIC values of 256 μg/mL against Escherichia coli standard and resistant strains, and 256 μg/mL and 32 μg/mL against Staphylococcus aureus standard and resistant strains, respectively. Two-dimensional (2D) Bi2WO6 nanosheets showed antibacterial efficiency against both strains studied without the presence of light. Conclusions: Layered Bi2WO6 nanosheets revealed dimension-dependent antibacterial activity of the Bi2WO6 system.