Details

Autor(en) / Beteiligte

• Fu, Yuan-Bo
• Li, Bin
• Sun, San-Feng
• Liu, Hui-Lin
• Wang, Xin
• Wang, Shao-Song
• Zhang, Fan
• Du, Xin
• Ge, Du-Juan
• Shang, Lei
• Liang, Rui-Li
• Wang, Li-Na
• Yuan, Fang
• Sun, Jing-Qing
• Chen, Jun-Wei

Titel

Fire acupuncture for mild to moderate knee osteoarthritis: a protocol for a randomized controlled pilot trial

Ist Teil von

• Trials, 2019-12, Vol.20 (1), p.673-673, Article 673

Ort / Verlag

England: BioMed Central Ltd

Erscheinungsjahr

2019

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Knee osteoarthritis (KOA) is one of the most common bone and joint diseases. As one of the main non-drug therapies, acupuncture is widely used to treat KOA, although the evidence for its efficacy is inconclusive. The objective of this pilot trial is to clarify the clinical efficacy and safety of fire acupuncture in the treatment of mild to moderate KOA and to provide high-quality data for further research. This study is a prospective randomized controlled pilot trial in which 120 patients with mild to moderate KOA will be randomly allocated in equal proportions to a fire acupuncture group or a general acupuncture group. They will receive acupuncture for six sessions over 2 weeks. The primary end point is success rate, which will be calculated based on the change from baseline of the pain and function scores in the Western Ontario and McMaster Universities Osteoarthritis Index at 4 weeks. Secondary end points include the proportion of patients achieving clinical improvement based on: (1) the OMERACT-OARSI responder criteria, (2) levels of matrix metalloproteinase 3, interleukin 1β, and tumor necrosis factor α in blood, and (3) a subjective efficacy evaluation from patients. Chinese Clinical Trial Registry, ChiCTR1800019162. Registered on 29 October 2018.