Details

Autor(en) / Beteiligte

• Cordes, Lisa M.
• Davarpanah, Nicole N.
• Reoma, Lauren B.
• Gasmi, Billel
• Quezado, Martha
• Khan, Omar I.
• Nath, Avindra
• Apolo, Andrea B.

Titel

Neurotoxicities associated with checkpoint inhibitors: Two case reports and a review of the literature

Ist Teil von

• Clinical case reports, 2020-01, Vol.8 (1), p.24-32

Ort / Verlag

England: John Wiley & Sons, Inc

Erscheinungsjahr

2020

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• We report a case of nivolumab‐induced delayed‐onset aseptic meningitis and a case of limbic encephalitis and peripheral nerve palsy with toxicity relapse 6 months after initial presentation. The atypical presentations contribute to our knowledge of these rare events and reinforce the necessity for vigilant monitoring and a multidisciplinary treatment approach. We report a case of nivolumab‐induced delayed‐onset aseptic meningitis and a case of limbic encephalitis and peripheral nerve palsy with toxicity relapse 6 months after initial presentation. The atypical presentations contribute to our knowledge of these rare events and reinforce the necessity for vigilant monitoring and a multidisciplinary treatment approach.