Details

Autor(en) / Beteiligte

• Curreri, Alexander M.
• Mitragotri, Samir
• Tanner, Eden E. L.

Titel

Recent Advances in Ionic Liquids in Biomedicine

Ist Teil von

• Advanced science, 2021-09, Vol.8 (17), p.e2004819-n/a

Ort / Verlag

Germany: John Wiley & Sons, Inc

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• The use of ionic liquids and deep eutectic solvents in biomedical applications has grown dramatically in recent years due to their unique properties and their inherent tunability. This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active pharmaceutical ingredients, delivery of pharmaceuticals through biological barriers, stabilization of proteins and other nucleic acids, antibacterial agents, and development of new biosensors. Current challenges and future outlooks are discussed, including biocompatibility, the potential impact of the presence of impurities, and the importance of understanding the microscopic interactions in ionic liquids in order to design task‐specific solvents. This review covers historical and recent advances of ionic liquids within the field of biomedicine. The article focuses on solubilization of drugs, active pharmaceutical ingredient ionic liquids, drug delivery, nanocarriers, protein stabilization, antimicrobial agents, and biosensing. The review also provides the future outlook and challenges for ionic liquids in the field of biomedical science.