Details

Autor(en) / Beteiligte

• Vaidya, Neel S
• Daneshmand, Arvin
• Epstein, Randy J
• Majmudar, Parag A
• Belin, Michael W
• Parsons, Edward C
• Rubinfeld, Roy S

Titel

Pachymetric Assessment After EpiSmart ® Epithelium-on Cross-Linking for Keratoconus and Post-Surgical Ectasia

Ist Teil von

• Clinical ophthalmology (Auckland, N.Z.), 2022-06, Vol.16, p.1829-1835

Ort / Verlag

New Zealand: Dove Medical Press Limited

Erscheinungsjahr

2022

Link zum Volltext

Quelle

Taylor & Francis Journals Auto-Holdings Collection

Beschreibungen/Notizen

• To assess the change in corneal pachymetry after a novel epithelium-on (EpiSmart ) corneal crosslinking procedure (CXL). Eyes treated as part of the open-label, non-controlled arm of the study "Collagen Crosslinking with Ultraviolet-A in Asymmetric Corneas" (NCT01097447) were examined at baseline, 3-, 6- and 12-months post-CXL. Thinnest pachymetry readings based on Pentacam (OCULUS GmbH, Wetzlar, Germany) were recorded. A total of 101 eyes met the study inclusion criteria. Thinnest pachymetric readings at baseline averaged 451 ± 50 microns. The mean (± SD) minimum thickness was 450 ± 46 microns at 3 months, 452 ± 47 microns at 6 months, and 451 ± 48 microns at 12 months post-CXL. The changes from baseline (mean ± SE) at 3, 6, and 12 months post-CXL were -1.2 ± 1.5 microns, 0.5 ± 1.6 microns, and 0.4 ± 1.6 microns, respectively. Student's t-tests showed no statistically significant change in pachymetry from baseline for any exam period. This study demonstrated that, after EpiSmart epithelium-on CXL, there was no substantial corneal thinning observable on Scheimpflug tomography out to 12 months.