Details

Autor(en) / Beteiligte

• Luo, Ma
• Zhang, Ling
• Jiang, Xin-Hua
• Zhang, Wei-Dong

Titel

Intravoxel Incoherent Motion Diffusion-weighted Imaging: Evaluation of the Differentiation of Solid Hepatic Lesions

Ist Teil von

• Translational oncology, 2017-10, Vol.10 (5), p.831-838

Ort / Verlag

United States: Neoplasia Press

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• To evaluate whether intravoxel incoherent motion (IVIM)-related parameters could be used to differentiate malignant from benign focal liver lesions (FLLs) and to improve diagnostic efficiency. Seventy-four patients with 75 lesions, including 51 malignant FLLs and 24 benign FLLs, underwent liver 3.0-T magnetic resonance imaging for routine examination sequences. IVIM diffusion-weighted imaging (DWI) with 11 b values (0-800s/mm ) was also acquired concurrently. Apparent diffusion coefficient (ADC ) and IVIM-derived parameters, such as the pure diffusion coefficient (D), the pseudodiffusion coefficient (D ), and the perfusion fraction (f), were calculated and compared between the two groups. A receiver operating characteristic curve analysis was performed to assess their diagnostic value. ADC , D, and f were significantly lower in the malignant group than in the benign group, whereas D did not show a statistical difference. D had a larger area under the curve value (0.968) and higher sensitivity (92.30%) for differentiation. IVIM is a useful method to differentiate malignant and benign FLLs. The D value showed higher efficacy to detect hepatic solid lesions.