Details

Autor(en) / Beteiligte

• Fujimoto, Eriko
• Yokoi, Takashi
• Mikami, Koji
• Kanemura, Shingo
• Shibata, Eisuke
• Horio, Daisuke
• Koda, Yuichi
• Negi, Yoshiki
• Akano, Yumiko
• Tada, Akio
• Minami, Toshiyuki
• Kuribayashi, Kozo
• Kijima, Takashi

Titel

Successful Treatment of Pulmonary Pleomorphic Carcinoma with Nivolumab: A Case Report

Ist Teil von

• Case reports in oncology, 2018-05, Vol.11 (2), p.336-340

Ort / Verlag

Basel, Switzerland: S. Karger AG

Erscheinungsjahr

2018

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Pulmonary pleomorphic carcinoma (PPC) has a poor prognosis due to the poor results of treatment with systemic chemotherapy. We report the case of a 73-year-old woman with PPC who showed a favorable response to nivolumab. As first-line treatment for postoperative recurrence, she received carboplatin and nanoparticle albumin-bound paclitaxel. However, 12 months later, a new metastatic lymph node appeared. Nivolumab was administered as second-line treatment, and the patient showed a favorable prolonged response. The effects of treatment of PPC with nivolumab seem promising. The results of a future prospective study are expected to identify indicators for the treatment of PPC.