Details

Autor(en) / Beteiligte

• HABA, Shiomi
• AONO, Yoshimi
• KON, Kyoko
• SAKURADA, Akira
• ENDO, Chiaki
• SAITO, Yasuki

Titel

Cytological features of reactive type II alveolar cells in broncho-alveolar lavage fluid

Ist Teil von

• The Journal of the Japanese Society of Clinical Cytology, 2019, Vol.58(4), pp.149-154

Ort / Verlag

The Japanese Society of Clinical Cytology

Erscheinungsjahr

2019

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Objective : Cytological specimens of bronchoalveolar lavage (BAL) fluid are a better resource to observe reactive type II alveolar cells than sputum, because of the lesser degree of cellular degenerative changes. The objective of this study was to specify the cytological characteristics of reactive type II alveolar cells.Study Design : We retrospectively reviewed the findings in BAL specimens obtained from 12 cases who had undergone bronchoscopy for the diagnosis of interstitial pneumonia or infection between April 2011 and July 2016.Results : Reactive type II alveolar cells were commonly observed as both small papillary-shaped clusters and as isolated cells. The cells had large nuclei, prominent nucleoli, and abundant cytoplasm with one or more of the following features ; foamy cytoplasm, cytoplasm having vacuoles of various sizes, or thick and monotonous cytoplasm having no vacuoles. Collagen globules and Mallory bodies were occasionally observed in the specimens.Conclusion : Careful evaluation is necessary for atypical cells appearing in the specimens of patients with various pulmonary inflammatory diseases. In this study, we outlined the cytological findings that would be helpful to distinguish reactive type II alveolar cells from adenocarcinoma cells.