Details

Autor(en) / Beteiligte

• Zhang, Guang Qiu
• Yang, Hai Ying
• Du, Gang
• Lai, Tian Chao
• Chen, Ming Hong
• Sun, Jing Xian

Titel

Microbial Hydroxylation of Progesterone with Phomopsis Sp

Ist Teil von

• Advanced materials research, 2013, Vol.781-784, p.1168-1171

Ort / Verlag

Trans Tech Publications Ltd

Erscheinungsjahr

2013

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Microbial hydroxylation of progesterone occurred in the biotransformation by Phomopsis sp.. The conversion products were purified by column chromatography with ether/EtOAc and characterized by spectroscopic methods including 1HNMR, 13C NMR, IR, UV and MS. Those conversion products were identified as 11α-hydroxyprogesterone (2), 11α,15β-dihydroxy progesterone (3),11α-dihydroxypreg-1,4-dien-3,20-dione (4), 6β,15βdihydroxypregesterone (5) and 7β,15βdihydroxypregesterone (6).