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The incidence of algae blooms is increasing in China and worldwide, causing serious environmental problem. A protozoan P1 was isolated from the water samples of Lake Dianchi, which had potent grazing effect on some kind of cyanobacteria. It should be belonged to Ciliophore, Oligohymenophorea, Philasterida based on morphological characters observed by the optical microscope. The main influencing factors of the protozoan grazing properties including: algae species, protozoan density, culture temperature, time and pH value were investigated in batch experiments. The results showed that the protozoan P1 had strong ability to graze the cells of Microcystis wesenbergii. The greater the initial protozoan density, the faster the degradation of chlorophyll-a. The removal rate of chlorophyll-a after 4 days was 78% at the optimum temperature 25°C, pH 7 when using a lower inoculation quantity of 2%. The protozoan P1 was easy to cultivate and reproduce rapidly. It could be applied in the ecological environment to control the Microcystis water bloom.