Details

Autor(en) / Beteiligte

• HASUI, Hiroki
• NISHIMURA, Koutarou
• IZUMORI, Akira
• KAJI, Yositeru
• SATOU, Akira

Titel

A case of primary biliary cirrhosis seronegative for anti-nuclear, anti-mitochodrial antibodies but positive for anti-smooth muscle antibody

Ist Teil von

• Kanzo, 2005, Vol.46(9), pp.563-569

Ort / Verlag

The Japan Society of Hepatology

Erscheinungsjahr

2005

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• We experienced a case of primary biliary cirrhosis (PBC) seronegative for anti-nuclear and anti-mitochondrial antibodies but positive for anti-smooth muscle antibody. She was a middle-aged woman and asymptomatic. Although laboratory data showed high titer of γ-globurin and IgG and modified AIH score (by International Autoimmune Hepatitis Group, 1999) was 14 which corresponded to probable AIH, she was histologically diagnosed as PBC by typical chronic non-suppurative destructive cholangitis and bile duct injury and lack of interface hepatitis. We think that measurement of anti-smooth muscle antibody may be useful to diagnose PBC in some cases but further studies will be needed to explain the significance of anti-smooth muscle antibody in PBC patients.