Details

Autor(en) / Beteiligte

• Malesevic, Milica
• Mihailovic, Jasna
• Vojicic, Jelena
• Popadic, Silvija

Titel

Early diagnosis, therapy, follow-up and survival rate of the patients with thyroid malignancy

Ist Teil von

• Acta chirurgica Iugoslavica, 2003, Vol.50 (3), p.177-183

Erscheinungsjahr

2003

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The Aim of the paper was to give a reviw of an early diagnosis, therapy, follow-up and survival rate of patients with thyroid malignancy (TM). The paper presented the algorithm of early diagnosis: clinical, scintigraphic and ultrasonographic examination together with fine needle biopsy, cythologic analysis of the smear and biopsy ex tempore of the clear and suspected thyroid node to malignancy. Therapy of all TM forms was mainly surgical; postsurgical treatment was dependent on the type of malignancy: radioiodine 131-I, radiologic treatment, chemotherapy and radioimmunotherapy, (the latest one being in the phase of a clinical research). Follow-up was in accordance with the protocole and it was necessary because it contributes to the survival rate. In the presentation of survival rate for differentiated and medullar carcinomas we gave our results and literature data, while for the other malignancies only data from literature were presented. Conclusion: only an early diagnosis of the nodular goiter together with an up-to-date treatment can cure TM patients in a high percentage and prevent development of a terminal stage of the desease which is extremely severe in all forms of this malignancy. Cilj rada je da se revijski prikaze rana dijagnostika, terapija, pracenje i prezivljavanje bolesnika sa tiroidnim malignitetom (TM). U radu je prikazan algoritam rane dijagnostike: klinicki, scintigrafski, ultrasongrafski pregled uz ciljanu punkciju, citolosku analizu punktata i uz biopsiju ex tempore tiroidnog nodusa jasnog ili sumnjivog na malignitet. Terapija je kod svih oblika TM primarno hirurska uz dodatno posthirursko lecenje, u zavisnosti od vrste maligniteta: radioaktivnim 131-I, radioloskim zracenjem, hemioterapijom i radioimunoterapjom (ova poslednja je tek u fazi klinickog ispitivanja). Pracenje bolesnika je po protokolu i neophodno je jer doprinosi boljem prezivljavanju. O prezivljavanju su prezentovani nasi rezultati i literaturni podaci za diferencirani i medularni karcinom, a za ostale malignitete samo literaturni podaci. Zakljucak: samo rana dijagnostika nodusne strume uz savremeni tretman, leci bolesnika od TM u vrlo visokom procentu i sprecava terminalni stadijum bolesti koji je izuzetno tezak kod svih oblika ovog maligniteta.