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The stress distribution underneath denture base and the resorption of alveolar bone are closely related to each other. In our recent studies with three-dimensional and two-dimensional finite element methods (2-D and 3-D FEM), the stress distribution was evaluated for removable dentures and their supporting structures. The purpose of this study was to validate the 3-D FEM and 2-D FEM models with experimental model as well as to compare the 3-D analysis with 2-D analysis. According to our results, the stress distribution of 3-D FEM was similar to the results of the experimental model. 2-D FEM tended to show exaggerated results compared with those 3-D FEM.