Details

Autor(en) / Beteiligte

• Moskalenko, R A
• Korneva, Yu S

Titel

Role of adipose tissue in the development and progression of colorectal cancer

Ist Teil von

• Arkhiv patologii, 2019, Vol.81 (1), p.52

Ort / Verlag

Russia (Federation)

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• The paper gives the current data available in the literature on the relationship and pathogenetic mechanisms of influence of adipose tissue on colorectal carcinogenesis. It considers the aspects of changes in adipose tissue and microenvironment of the tumor itself, including those under the influence of biologically active substances secreted by adipocytes; differences in subcutaneous and visceral fat and their importance in the development and progression of colorectal cancer (CRC), as well as the role of adipose tissue-derived stem cells. Understanding these mechanisms for adipose tissue influence on CRC will assist not only in preventing this disease, but also in searching for new therapeutic targets.