The International journal of developmental biology, 2018, Vol.62 (1-2-3), p.121-126
2018
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Details
- Autor(en) / Beteiligte
- Titel
- A snail tale and the chicken embryo
- Ist Teil von
- The International journal of developmental biology, 2018, Vol.62 (1-2-3), p.121-126
- Ort / Verlag
- Spain
- Erscheinungsjahr
- 2018
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Some 25 years ago, a clone was identified that contained the chicken Slug sequences (now called Snail2 ). How could we anticipate at that time how much the chick embryo would help us to understand the ins and outs of cell migration during development and in disease? Indeed, the chick embryo helped us identify Snail2 as the first transcription factor that could induce the epithelial-mesenchymal transition (EMT), key for the migration of embryonic and cancer cells.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0214-6282eISSN: 1696-3547DOI: 10.1387/ijdb.170301mnTitel-ID: cdi_crossref_primary_10_1387_ijdb_170301mn
- Format
- –
- Schlagworte
- Animals, Cadherins - metabolism, Cell Line, Tumor, Cell Movement, Chick Embryo, Chickens, Disease Progression, Embryology - history, Embryology - methods, Epithelial-Mesenchymal Transition, Gene Expression Profiling, Gene Expression Regulation, Developmental, History, 20th Century, History, 21st Century, Humans, Neoplasms - pathology, Neural Crest - physiology, Promoter Regions, Genetic, Snail Family Transcription Factors - genetics, Snail Family Transcription Factors - physiology, Transcription Factors