Details

Autor(en) / Beteiligte

• Ma, Zhenhe
• Liu, Xiaodi
• Yin, Bin
• Zhao, Yuqian
• Liu, Jian
• Yu, Yao
• Wang, Yi

Titel

Common-path-based device for magnetomotive OCT noise reduction

Ist Teil von

• Applied optics (2004), 2020-02, Vol.59 (5), p.1431

Ort / Verlag

United States

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• Magnetomotive optical coherence tomography (MMOCT) is a promising imaging method for noninvasive three-dimensional tracking of magnetic nanoparticle (MNP) motions in target tissues or organs. The external -field is the driving force that provides MMOCT contrast. However, -field modulation also introduces modulation noise, thereby decreasing the quality of the MMOCT image. In this paper, a common-path-based device is designed for modulation noise reduction. The device is capable of adjusting interference distance, reference light intensity, and imaging position ( - translation). The sensitivity of the MMOCT is increased by ∼20 times with the new device. Using the proposed device, the distribution of MNPs injected in zebrafish was imaged.