Details

Autor(en) / Beteiligte

• Thanh, Nguyen Ha
• Phuong, Hoang Thi
• Giang, Le Nhat Thuy
• Giang, Nguyen Thi Quynh
• Ha, Nguyen Thi Thu
• Anh, Dang Thi Tuyet
• Cuong, Vu Duc
• Van Tuyen, Nguyen
• Van Kiem, Phan

Titel

4-(Dimethylamino)pyridine as an Efficient Catalyst for One-Pot Synthesis of 1,4-Pyranonaphthoquinone Derivatives via Microwave-Assisted Sequential Three Component Reaction in Green Solvent

Ist Teil von

• Natural product communications, 2021-11, Vol.16 (11), p.1934578

Ort / Verlag

Los Angeles, CA: SAGE Publications

Erscheinungsjahr

2021

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Novel 1,4-pyranonaphthoquinone derivatives were successfully synthesized via the microwave-assisted three-component reaction of 1,4-naphthoquinone, malononitrile, and various arylaldehydes in ethanol in the presence of 4-(dimethylamino)pyridine (DMAP) as a catalyst, and subsequently evaluated in terms of their antimicrobial and antifungal activities. This synthetic procedure has the notable advantages of environmental friendliness, short reaction time, good yield, and convenient operation.