Details

Autor(en) / Beteiligte

• Lo, Eng H
• Albers, Gregory W
• Dichgans, Martin
• Donnan, Geoffrey
• Esposito, Elga
• Foster, Russell
• Howells, David W
• Huang, Yi-Ge
• Ji, Xunming
• Klerman, Elizabeth B
• Lee, Sarah
• Li, Wenlu
• Liebeskind, David S
• Lizasoain, Ignacio
• Mandeville, Emiri T
• Moro, Maria A
• Ning, MingMing
• Ray, David
• Sakadžić, Sava
• Saver, Jeffrey L
• Scheer, Frank A J L
• Selim, Magdy
• Tiedt, Steffen
• Zhang, Fang
• Buchan, Alastair M

Titel

Circadian Biology and Stroke

Ist Teil von

• Stroke (1970), 2021-06, Vol.52 (6), p.2180-2190

Ort / Verlag

United States

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• Circadian biology modulates almost all aspects of mammalian physiology, disease, and response to therapies. Emerging data suggest that circadian biology may significantly affect the mechanisms of susceptibility, injury, recovery, and the response to therapy in stroke. In this review/perspective, we survey the accumulating literature and attempt to connect molecular, cellular, and physiological pathways in circadian biology to clinical consequences in stroke. Accounting for the complex and multifactorial effects of circadian rhythm may improve translational opportunities for stroke diagnostics and therapeutics.