Case reports in oncology, 2018-02, Vol.11 (1), p.109-113
2018
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Details
- Autor(en) / Beteiligte
- Titel
- Concomitant Non-Small Cell Lung Cancer and Hairy Cell Leukemia in a Patient Harboring BRAF-V600E Mutation in Both Tissues: A Case Report
- Ist Teil von
- Case reports in oncology, 2018-02, Vol.11 (1), p.109-113
- Ort / Verlag
- Basel, Switzerland: S. Karger AG
- Erscheinungsjahr
- 2018
- Quelle
- EZB Electronic Journals Library
- Beschreibungen/Notizen
- The BRAF-V600E mutation has been established as a signature alteration occurring almost universally in hairy cell leukemia. Moreover, it can be detected in a small percentage of patients with non-small cell lung cancer. We report the case of a patient with a metastatic BRAF-V600E-mutated lung adenocarcinoma suffering from concomitant hairy cell leukemia. The identification of an identical BRAF mutation in both malignancies raises physiopathological considerations and might offer unique therapeutic strategies for this group of patients.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1662-6575eISSN: 1662-6575DOI: 10.1159/000486640Titel-ID: cdi_crossref_primary_10_1159_000486640
- Format
- –
- Schlagworte
- Anemia, Bone marrow, BRAF-V600E mutation, Cancer therapies, Case Report, Case reports, Cell cycle, Colorectal cancer, Disease, Driver mutations, Esophagus, Hairy cell leukemia, Immunotherapy, Kinases, Leukemia, Lung adenocarcinoma, Lung cancer, Melanoma, Mutation, Neutrophils, Non-small cell lung cancer, Skin cancer, Tumors