Details

Autor(en) / Beteiligte

• Mahmud, Mohammad Sultan
• Cadotte, David W
• Vuong, Barry
• Sun, Carry
• Luk, Timothy W. H
• Mariampillai, Adrian
• Yang, Victor X. D

Titel

Review of speckle and phase variance optical coherence tomography to visualize microvascular networks

Ist Teil von

• Journal of biomedical optics, 2013-05, Vol.18 (5), p.050901-050901

Ort / Verlag

United States: Society of Photo-Optical Instrumentation Engineers

Erscheinungsjahr

2013

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• High-resolution mapping of microvasculature has been applied to diverse body systems, including the retinal and choroidal vasculature, cardiac vasculature, the central nervous system, and various tumor models. Many imaging techniques have been developed to address specific research questions, and each has its own merits and drawbacks. Understanding, optimization, and proper implementation of these imaging techniques can significantly improve the data obtained along the spectrum of unique research projects to obtain diagnostic clinical information. We describe the recently developed algorithms and applications of two general classes of microvascular imaging techniques: speckle-variance and phase-variance optical coherence tomography (OCT). We compare and contrast their performance with Doppler OCT and optical microangiography. In addition, we highlight ongoing work in the development of variance-based techniques to further refine the characterization of microvascular networks.