Details

Autor(en) / Beteiligte

• Shaddox, Luciana Macchion
• Morford, Lorri Ann
• Nibali, Luigi

Titel

Periodontal health and disease: The contribution of genetics

Ist Teil von

• Periodontology 2000, 2021-02, Vol.85 (1), p.161-181

Ort / Verlag

Denmark

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• Periodontitis is an infectious, inflammatory disease that is associated with a complex interplay between specific bacteria, host response, and environmental factors. Because of its high degree of familial aggregation, specifically for the more aggressive forms of the disease, genetics factors have been implicated in disease pathogenesis for several decades. This review provides an overview of what we currently know regarding the genetic and epigenetic contributions to periodontal disease and discusses future opportunities in the field.