Details

Autor(en) / Beteiligte

• Burgos, Ninon
• Cardoso, M. Jorge
• Thielemans, Kris
• Modat, Marc
• Pedemonte, Stefano
• Dickson, John
• Barnes, Anna
• Ahmed, Rebekah
• Mahoney, Colin J.
• Schott, Jonathan M.
• Duncan, John S.
• Atkinson, David
• Arridge, Simon R.
• Hutton, Brian F.
• Ourselin, Sebastien

Titel

Attenuation Correction Synthesis for Hybrid PET-MR Scanners: Application to Brain Studies

Ist Teil von

• IEEE transactions on medical imaging, 2014-12, Vol.33 (12), p.2332-2341

Ort / Verlag

United States: IEEE

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not directly provide a patient-specific attenuation map. The aim of the proposed work is to improve attenuation correction for PET/MR scanners by generating synthetic CTs and attenuation maps. The synthetic images are generated through a multi-atlas information propagation scheme, locally matching the MRI-derived patient's morphology to a database of MRI/CT pairs, using a local image similarity measure. Results show significant improvements in CT synthesis and PET reconstruction accuracy when compared to a segmentation method using an ultrashort-echo-time MRI sequence and to a simplified atlas-based method.