Details

Autor(en) / Beteiligte

• Núñez-Pizarro, Jorge L
• González-Luna, Alejandro
• Mezones-Holguín, Edward
• Blümel, Juan E
• Barón, Germán
• Bencosme, Ascanio
• Benítez, Zully
• Bravo, Luz M
• Calle, Andrés
• Flores, Daniel
• Espinoza, María T
• Gómez, Gustavo
• Hernández-Bueno, José A
• Martino, Mabel
• Lima, Selva
• Monterrosa, Alvaro
• Mostajo, Desiree
• Ojeda, Eliana
• Onatra, William
• Sánchez, Hugo
• Tserotas, Konstantinos
• Vallejo, María S
• Witis, Silvina
• Zúñiga, María C
• Chedraui, Peter

Titel

Association between anxiety and severe quality-of-life impairment in postmenopausal women: analysis of a multicenter Latin American cross-sectional study

Ist Teil von

• Menopause (New York, N.Y.), 2017-06, Vol.24 (6), p.645-652

Ort / Verlag

United States

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• To evaluate associations between anxiety and severe impairment of quality of life (QoL) in Latin American postmenopausal women. This was a secondary analysis of a multicenter cross-sectional study among postmenopausal women aged 40 to 59 from 11 Latin American countries. We evaluated anxiety (The Goldberg Depression and Anxiety Scale), and QoL (Menopause Rating Scale [MRS]), and included sociodemographic, clinical, lifestyle, and anthropometric variables in the analysis. Poisson family generalized linear models with robust standard errors were used to estimate prevalence ratios (PRs) and 95% CIs. There were two adjusted models: a statistical model that included variables associated with the outcomes in bivariate analyses, and an epidemiologic model that included potentially confounding variables from literature review. Data from 3,503 women were included; 61.9% had anxiety (Goldberg). Severe QoL impairment (total MRS score ≥17) was present in 13.7% of women, as well as severe symptoms (MRS subscales): urogenital (25.5%), psychological (18.5%), and somatic (4.5%). Anxiety was independently associated with severe QoL impairment and severe symptoms in the epidemiological (MRS total score: PR 3.6, 95% CI, 2.6-5.0; somatic: 5.1, 95% CI, 2.6-10.1; psychological: 2.8, 95% CI, 2.2-3.6; and urogenital: 1.4, 95% CI, 1.2-1.6) and the statistical model (MRS total score: PR 3.5, 95% CI, 2.6-4.9; somatic: 5.0, 95% CI, 2.5-9.9; psychological: 2.9, 95% CI, 2.2-3.7; and urogenital: 1.4; 95% CI, 1.2-1.6). In this postmenopausal Latin American sample, anxiety was independently associated with severe QoL impairment. Hence, screening for anxiety in this population is important.