Details

Autor(en) / Beteiligte

• Wu, Sean Z
• Muddasani, Suraj
• Alam, Murad

Titel

A Systematic Review of the Efficacy and Safety of Microneedling in the Treatment of Melasma

Ist Teil von

• Dermatologic surgery, 2020-12, Vol.46 (12), p.1636-1641

Ort / Verlag

United States: by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• BACKGROUNDMelasma is an acquired disorder of hyperpigmentation that is often recalcitrant to current therapies. Microneedling is used to treat scars, striae, and rhytides and has a relatively low risk of post-treatment dyspigmentation. Several studies have examined its use in melasma. OBJECTIVETo review the published evidence on the efficacy and safety of microneedling in the treatment of melasma. METHODSA systematic review was performed. A meta-analysis could not be performed because of methodological differences across studies and data heterogeneity. RESULTSEight studies were included for analysis. Most studies assessed the utility of microneedling in combination with other topical therapies and detected some success. However, microneedling-mediated transdermal delivery of medications is not superior to microinjections of medications. There is less evidence supporting the use of microneedling as monotherapy. Microneedling, when used with a 1064-nm Q-switched Nd:YAG laser, may provide additional benefit, although with a risk of post-treatment dyspigmentation. CONCLUSIONBased on low-quality evidence, microneedling may play a role in the treatment of melasma, with the mechanism of action likely being the facilitation of delivery of topical therapies to the epidermis and dermis, and one ancillary benefit of this approach being the very low risk of postinflammatory hyperpigmentation.