Details

Autor(en) / Beteiligte

• Noronha, Jarvis Clyde
• Choo, Vivian
• Mejia, Sonia Blanco
• Viguiliouk, Effie
• Jayalath, Viranda
• Braunstein, Catherine
• Kendall, Cyril WC
• Sievenpiper, John

Titel

Liquid Calories from Sugars Do Not Increase Body Weight More than Solid Calories: A Systematic Review and Meta‐Analysis of Controlled Feeding Trials

Ist Teil von

• The FASEB journal, 2016-04, Vol.30 (S1)

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Wiley Online Library

Beschreibungen/Notizen

• Abstract only Objective Although liquid calories from sugars have been shown to be more poorly compensated than solid calories in pooled analyses of acute preload trials, it is unclear whether they contribute more to weight gain over the longer term. To synthesize the evidence of the effect of liquid calories from sugars versus solid calories on body weight in controlled trials. Methods We searched Medline, EMBASE, and Cochrane Library through September 21, 2015. We included controlled trials of ≥ 7 days investigating the effect of liquid calories from sugars in exchange for solid calories from various sources on body weight. Two independent reviewers extracted relevant data as well as assessed risk of bias (Cochrane Risk of Bias Tool). Data were pooled using the generic inverse variance method and expressed as mean differences (MD) with 95% confidence intervals (CIs). Heterogeneity was assessed (Cochran Q statistic) and quantified (I 2 statistic). Results Seven trials involving 135 participants met the eligibility criteria. The exchange of liquid calories from sugars for solid calories from various carbohydrates did not lead to significant weight gain (MD= −0.38 kg (95% CI −2.14 kg to 1.37 kg) over a median follow‐up of 6‐weeks. There was no evidence of inter‐study heterogeneity (I 2 = 0%). Limitations The small number and short duration of the available trials are important sources of uncertainty. Conclusion Pooled analyses failed to show that liquid calories from sugars result in weight gain compared to solid calories from different carbohydrates. There remains a need for larger and longer high quality trials. Support or Funding Information Funding: The Canadian Institutes of Health Research (funding reference number, 129920) through the Canada‐wide Human Nutrition Trialists’ Network (NTN) and PSI foundation.