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Treatment of Vacutainers for Use in the Analysis of Volatile Organic Compounds in Human Blood at the Low Parts-Per-Tri11ion Level
Ist Teil von
Journal of chromatographic science, 1995-10, Vol.33 (10), p.557-560
Ort / Verlag
Oxford University Press
Erscheinungsjahr
1995
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Vacutainers that are routinely used for blood collection contain significant amounts of volatile organic compounds (VOCs). These VOCs interfere with the low parts-per-trillion analysis of VOCs in whole blood either by causing false positives or by masking the presence of VOCs because of high background levels. Benzene, bromoform, ethylbenzene, m/p-xylene, o-xylene, styrene, and various hydrocarbons are the most significant sources of VOC contamination present in the vacutainers. A method of removing VOCs from 10-mL gray-top vacutainers is presented. This method uses a combination of heat and vacuum to reduce the VOCs to levels compatible with low parts-per-trillion analysis of VOCs in whole blood.