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Electronic cigarette exposure reduces exercise performance and changes the biochemical profile of female mice
Ist Teil von
Bioscience, biotechnology, and biochemistry, 2019-12, Vol.83 (12), p.2318-2326
Ort / Verlag
England: Taylor & Francis
Erscheinungsjahr
2019
Link zum Volltext
Quelle
Free E-Journal (出版社公開部分のみ)
Beschreibungen/Notizen
Electronic cigarette(s) (EC) becoming a preferred replacement for nicotine delivery among many smokers in recent years. However, the effect of EC on human health is inconclusive due to a lack of empirical research investigating EC-induced health hazard or benefit. In this study, we examine the effect of vapor produced by EC on exercise performance and health-related profiles in a mouse model. Female ICR mice were divided into five groups (n = 6 per group) and exposed for 14 days. Our results indicate that EC exposure leads to dose-dependent decrease in the grip strength and swimming time of the mice. The EC-treated groups also showed a dose-dependent decrease in liver and muscle glycogen storage. In addition, EC treatment had no negative effect on levels of biochemical indices. We also did not detect any adverse effect or gross abnormalities on the morphology of the major organs.
EC exposure leads to dose-dependent decrease in exercise performance (endurance and explosiveness) and glycogen storage capacity of the mice.