Details

Autor(en) / Beteiligte

• Rihova, Zuzana
• Maixnerova, Dita
• Jancova, Eva
• Pelclova, Daniela
• Bartunkova, Jirina
• Fenclova, Zdenka
• Vankova, Zdenka
• Reiterova, Jana
• Merta, Miroslav
• Rysava, Romana
• Tesar, Vladimir

Titel

Silica and Asbestos Exposure in ANCA-Associated Vasculitis with Pulmonary Involvement

Ist Teil von

• Renal failure, 2005, Vol.27 (5), p.605-608

Ort / Verlag

Colchester: Informa UK Ltd

Erscheinungsjahr

2005

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Silica and asbestos exposure are thought to belong to the triggering factors of antineutrophil cytoplasm antibodies (ANCA)-associated vasculitis. We carried out a study to find out whether patients with pulmonary involvement attributable to ANCA-associated vasculitis (AAV) have been exposed to silicon-containing materials. Thirty-one patients (12 women, 19 men, median age 51 years) were interviewed using a structured questionnaire. Occupational exposure to silicon-containing chemicals was reported by 22.6% of the patients (12.9% to SiO2, 9.7% to asbestos), compared with 0% of control subjects (p < 0.05). Our findings support the pathophysiologic role of silica in AAV.