Details

Autor(en) / Beteiligte

• Konjevic, D
• Srebocan, E
• Gudan, A
• Lojkic, I
• Severin, K
• Sokolovic, M

Titel

pathological condition possibly caused by spontaneous trichotecene poisoning in Brahma poultry: first report

Ist Teil von

• Avian pathology, 2004-06, Vol.33 (3), p.377-380

Ort / Verlag

England

Erscheinungsjahr

2004

Quelle

MEDLINE

Beschreibungen/Notizen

• Trichotecene poisoning in poultry can cause oral lesions, haemorrhages, depletion and necrosis in the lymphopoetic organs and death. Spontaneous poisonings with these toxins are rarely described. This paper describes the spontaneous poisoning of two Brahma chickens with T-2 toxin, diacetoxyscirpenol and deoxynivalenol. Two out of 10 chickens died under signs of depression and loss of appetite. Histopathological analysis revealed vacuolar dystrophy of the liver, necrosis and depletion of lymphocyte in the bursa of Fabricius as well as multiple necroses in the glandular stomach and gut. Even though quantities of 0.70 mg/kg T-2 in the food together with 0.50 mg/kg diacetoxyscirpenol significantly differ from the median lethal dose for chickens reported in literature (4.97 mg/kg), parasitological, virological and histopathological results indicate trichotecenes as the causative agents of this pathological condition.