Details

Autor(en) / Beteiligte

• Lee, Geon-Woo
• Park, Jeong-Yeol
• Kim, Dae-Yeon
• Suh, Dae-Shik
• Kim, Jong-Hyeok
• Kim, Yong-Man
• Kim, Young-Tak
• Nam, Joo-Hyun

Titel

Usefulness of sentinel lymph node mapping using indocyanine green and fluorescent imaging in the diagnosis of lymph node metastasis in endometrial cancer

Ist Teil von

• Journal of obstetrics and gynaecology, 2021-05, Vol.41 (4), p.605-611

Ort / Verlag

England: Taylor & Francis

Erscheinungsjahr

2021

Beschreibungen/Notizen

• The lymph node status is the most important prognostic factor for endometrial cancer. This study aimed to assess whether sentinel lymph node mapping (SLNM) is applicable in endometrial cancer. A retrospective review of patients with endometrial cancer who were diagnosed and treated in Asan Medical Centre from September 2015 to December 2017 was conducted. One hundred patients underwent robotic (da Vinci®) or laparoscopic surgical treatment, including SLNM with indocyanine green (ICG) fluorescence detection using the Firefly® and NIR/ICG systems. At least one lymph node area was observed in 100% of SLNM cases. Sentinel node detection and frozen biopsy were performed in all cases, and all patients with metastasis were found on SLNM. The sensitivity and negative predictive value were both 100% in the patient-by-patient and station-by-station analyses. SLNM appears to be a feasible method to reduce the morbidity and increase the detection rate in early-stage endometrial carcinoma. What is already known on this subject? There are studies that it is safe to diagnose the possibility of lymph node metastasis through sentinel lymph node mapping in endometrial cancer. What do the results of this study add? In this study, it is shown that the accuracy of sentinel lymph node mapping is 100% accurate. What are the implications of these findings for clinical practise and/or further research? Therefore, total lymphadenectomy will not be necessary for the future.