Details

Autor(en) / Beteiligte

• Jones, R. Alan
• Rustidge, David C.
• Cushman, Susan M.

Titel

A. Critical Evaluation of the Knorr Synthesis of Tpifluoromethylpyrroles and the Reactivity of Diethyl 4-Trifluoromethyl-2-Methylpyrrole-3, 5-Dicarboxylate

Ist Teil von

• Synthetic communications, 1984-05, Vol.14 (6), p.575-584

Ort / Verlag

Taylor & Francis Group

Erscheinungsjahr

1984

Quelle

Taylor & Francis

Beschreibungen/Notizen

• β-Trifluoromethyl pyrroles are readily obtained by the Knorr synthesis, but the procedure fails for the preparation of the the α-isomers. The β-trifluoromethyl group reacts with alkoxide anions and is reduced with lithium aluminium hydride.