Details

Autor(en) / Beteiligte

• da Silva, Joaquim F. M.
• Yepes Perez, Andres F.
• de Almeida, Natália P.

Titel

Phosphine-Free Suzuki Cross-Coupling Reaction Using an Efficient and Reusable Pd Catalyst in an Aqueous Medium Under Microwave Irradiation

Ist Teil von

• Synthetic communications, 2015-09, Vol.45 (17), p.1995-2004

Ort / Verlag

Philadelphia: Taylor & Francis

Erscheinungsjahr

2015

Quelle

AUTh Library subscriptions: Taylor & Francis Journals

Beschreibungen/Notizen

• We report here an improved, highly efficient, and general method for the ligand-free Suzuki cross-coupling reaction to the synthesis of biaryls, bipyridyls, thienylpyridine, and allylphenols. Microwave irradiation of (het)aryl halides and (hetaryl, allyl)arylboronic acid N-methyl-iminodiacetic acid (MIDA) ester, using polyurea microencapsulated palladium catalyst (Pd EnCat 30), gave the coupling adducts 1a-x in excellent yields in just 10-18 min.