Details

Autor(en) / Beteiligte

• Rühl, Thomas
• Böttcher, Christoph
• Pumpor, Ksenia
• Hennig, Lothar
• Sieler, Joachim
• Burger, Klaus

Titel

Hexafluoroacetone as Protecting and Activating Reagent: Site-Selective Functionalization of α-Amino Alkanedioic Acids

Ist Teil von

• Synthesis (Stuttgart), 2004-12, Vol.2004 (18), p.3065-3069

Erscheinungsjahr

2004

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Abstract Methodology for the site-selective functionalization of α-amino alkanedioic acids (Asp, Glu and homologues) using hexa­fluoroacetone as protecting and activating reagent is described. Via new types of dielectrophiles, alternative approaches to multifunctional non-natural amino acids and some of their conjugates become readily available.