Details

Autor(en) / Beteiligte

• Jurinic, Carla K.
• Belladona, Andrei L.
• Schumacher, Ricardo F.
• Godoi, Benhur

Titel

Diorganyl Dichalcogenides and Copper/Iron Salts: Versatile Cyclization System To Achieve Carbo- and Heterocycles from Alkynes

Ist Teil von

• Synthesis (Stuttgart), 2021-08, Vol.53 (15), p.2545-2558

Erscheinungsjahr

2021

Beschreibungen/Notizen

• Abstract Organochalcogen-containing cyclic molecules have shown several promising pharmacological properties. Consequently, different strategies have been developed for their synthesis in the past few years. Particularly due to the low cost and environmental aspects, copper- and iron-promoted cyclization reactions of alkynyl substrates have been broadly and efficiently applied for this purpose. This short review presents an overview of the most recent advances in the synthesis of organochalcogen-containing carbo- and heterocycles by reacting diorganyl disulfides, diselenides, and ditellurides with alkyne derivatives in the presence of copper and iron salts to promote cyclization reactions. 1 Introduction 2 Synthesis of Carbo- and Heterocycles via Reactions of Alkynes with Diorganyl Dichalcogenides and Copper Salts 3 Synthesis of Carbo- and Heterocycles via Reactions of Alkynes with Diorganyl Dichalcogenides and Iron Salts 4 Conclusions