Details

Autor(en) / Beteiligte

• Zhang, Zhipeng
• Ye, Huan
• Cai, Fei
• Sun, Yao

Titel

Recent advances on the construction of long-wavelength emissive supramolecular coordination complexes for photo-diagnosis and therapy

Ist Teil von

• Dalton transactions : an international journal of inorganic chemistry, 2023-10, Vol.52 (42), p.15193-1522

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Recently, metal-based drugs have attracted relentless interest in the biomedical field. However, their short excitation/emission wavelengths and unsatisfactory therapeutic efficiency limit their biological applications in vivo . Currently, the second near-infrared window (NIR-II, 1000-1700 nm) provides more accurate imaging and therapeutic options. Thus, there has been a constant focus on developing multifunctional NIR metal agents for imaging and therapy that have deeper tissue penetration. Fortunately, supramolecular coordination complexes (SCCs) formed by the coordination-driven self-assembly of NIR-II emissive ligands can address the above issues. Importantly, metal receptors with chemotherapeutic properties in SCCs can bind to luminescent ligands, thus becoming a versatile therapeutic platform for chemotherapy, imaging and phototherapy. In this context, we systematically summarize the evolution of NIR-II emissive SCCs for biomedical applications and discuss future challenges and prospects. Schematic diagram of the diagnosis and treatment of NIR-II emissive SCCs.