Details

Autor(en) / Beteiligte

• Yuan, Jin-Wei
• Chen, Qian
• Li, Chuang
• Zhu, Jun-Liang
• Yang, Liang-Ru
• Zhang, Shou-Ren
• Mao, Pu
• Xiao, Yong-Mei
• Qu, Ling-Bo

Titel

Silver-catalyzed direct C-H oxidative carbamoylation of quinolines with oxamic acids

Ist Teil von

• Organic & biomolecular chemistry, 2020-04, Vol.18 (14), p.2747-2757

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A silver-catalyzed efficient and direct C-H carbamoylation of quinolines with oxamic acids to access carbamoylated quinolines has been developed through oxidative decarboxylation reaction. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance and excellent yields under mild conditions. A facile and highly efficient method has been successfully developed for the synthesis of 2-carbamoylated quinolines. The current reaction exhibits broad substrate scope, good functional group compatibility, and good to excellent yields.